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Minimal Cytotoxicity of Water-Soluble SiQDs with Blood Plasma Proteins Interaction

Prof. C. Shanmugavel et al., and his research collaboration team (from various universities at Japan) have been investigated on the interaction of blood plasma proteins and water-soluble silicon quantum dots (SiQDs) for the minimal cytotoxicity. This research investigation was reported in nanomaterials of MDPI publication journal and published on  13 th  November 2020. In this research article, they have reported on the conformational changes of blood plasma proteins during the interaction with near-infrared light-emitting nanoparticles, which comprised with assembled Pluronic-F127 coated semiconductor (silicon) QDs terminated with decane monolayers.   The semiconductor QDs have chosen as an alternative, owing to its high quantum yield and low photo bleaching characters by various researchers and scientists. Other previous research studies have also showed that the QDs has exhibited a molecular interaction with various proteins, which consists of toxic heavy metal ions (...